Article
Leptin signaling.
Physiology & behavior - 1 Apr 2004
Ahima Rexford S, Osei Suzette Y
Abstract excerpt
The discovery of leptin was a major breakthrough in our understanding of the role of adipose tissue as a storage and secretory organ. Leptin was initially thought to act mainly to prevent obesity; however, studies have demonstrated profound effects of leptin in the response to fasting, regulation of neuroendocrine and immune systems, hematopoiesis, bone and brain development. This review will focus on the...
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