Article
Distribution of allelic and genotypic frequencies of IL1A, IL4, NFKB1 and PAR1 variants in Native American, African, European and Brazilian populations.
BMC research notes - 16 Feb 2016
Amador Marcos A T, Cavalcante Giovanna C, Santos Ney P C, Gusmão Leonor, Guerreiro João F, Ribeiro-dos-Santos Ândrea, Santos Sidney
Abstract excerpt
BACKGROUND: The inflammatory response plays a key role at different stages of cancer development. Allelic variants of the interleukin 1A (IL1A), interleukin 4 (IL4), nuclear factor kappa B1 (NFKB1) and protease-activated receptor 1 (PAR1) genes may influence not only the inflammatory response but also susceptibility to cancer development. Among major ethnic or continental groups, these polymorphic variants...
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