Article
Genetic ancestry modifies the association between genetic risk variants and breast cancer risk among Hispanic and non-Hispanic white women.
Carcinogenesis - 1 Aug 2013
Fejerman Laura, Stern Mariana C, Ziv Elad, John Esther M, Torres-Mejia Gabriela, Hines Lisa M, Wolff Roger, Wang Wei, Baumgartner Kathy B, Giuliano Anna R, Slattery Martha L
Abstract excerpt
Hispanic women in the USA have lower breast cancer incidence than non-Hispanic white (NHW) women. Genetic factors may contribute to this difference. Breast cancer genome-wide association studies (GWAS) conducted in women of European or Asian descent have identified multiple risk variants. We tested the association between 10 previously reported single nucleotide polymorphisms (SNPs) and risk of breast cancer in a...
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