Article
Contrasting evolution of the human leukocyte N-formylpeptide receptor subtypes FPR and FPRL1R.
Genes and immunity - 1 Oct 2001
Sahagun-Ruiz A, Colla J S, Juhn J, Gao J L, Murphy P M, McDermott D H
Abstract excerpt
N-formylpeptides are phagocyte chemoattractants that act by binding to two structurally related receptors, FPR (formylpeptide receptor) and FPRL1R (FPR-like-1 receptor), which are encoded by the human genes FPR1 and FPRL1. Single nucleotide polymorphisms (SNPs) in the FPR coding region have been reported and two have been associated with the disease juvenile periodontitis; however, their frequency and linkage...
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