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Article

Influence of Genetic Ancestry on INDEL Markers of NFKβ1, CASP8, PAR1, IL4 and CYP19A1 Genes in Leprosy Patients.

PLoS neglected tropical diseases - 1 Jan 2015

Pinto Pablo, Salgado Claudio, Santos Ney Pereira Carneiro, Santos Sidney, Ribeiro-dos-Santos Ândrea

Abstract excerpt

BACKGROUND: Leprosy is an insidious infectious disease caused by the obligate intracellular bacteria Mycobacterium leprae, and host genetic factors can modulate the immune response and generate distinct categories of leprosy susceptibility that are also influenced by genetic ancestry. METHODOLOGY/PRINCIPAL FINDINGS: We investigated the possible effects of CYP19A1 [rs11575899], NFKβ1 [rs28362491], IL1α...

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Source

Open in PubMed Open full text

Identifiers

PMID: 26367014
DOI: 10.1371/journal.pntd.0004050
PMCID: PMC4569399

Genes

CASP8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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