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Article

Aging and ABO blood type influence von Willebrand factor and factor VIII levels through interrelated mechanisms.

Journal of thrombosis and haemostasis : JTH - 1 May 2016

Albánez S, Ogiwara K, Michels A, Hopman W, Grabell J, James P, Lillicrap D

Abstract excerpt

UNLABELLED: Essentials von Willebrand factor (VWF) and factor VIII (FVIII) levels are modulated by age and ABO status. The effect of aging and ABO blood type on VWF and FVIII was assessed in 207 normal individuals. Aging and ABO blood type showed combined and bidirectional influences on VWF and FVIII levels. Aging and ABO blood type influence VWF levels through both secretion and clearance mechanisms. SUMMARY:...

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Share to ABO Blood-Group System
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26875505
DOI: 10.1111/jth.13294
PMCID: PMC5949873

Genes

VWF
ABO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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