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Article

Quantitative Influence of ABO Blood Groups on Factor VIII and Its Ratio to von Willebrand Factor, Novel Observations from an ARIC Study of 11,673 Subjects.

PloS one - 1 Jan 2015

Song Jaewoo, Chen Fengju, Campos Marco, Bolgiano Doug, Houck Katie, Chambless Lloyd E, Wu Kenneth K, Folsom Aaron R, Couper David, Boerwinkle Eric, Dong Jing-fei

Abstract excerpt

ABO blood groups are known to influence the plasma level of von Willebrand factor (VWF), but little is known about the relationship between ABO and coagulation factor VIII (FVIII). We analyzed the influence of ABO genotypes on VWF antigen, FVIII activity, and their quantitative relationship in 11,673 participants in the Atherosclerosis Risk in Communities (ARIC) study. VWF, FVIII, and FVIII/VWF levels varied...

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Source

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Identifiers

PMID: 26244499
DOI: 10.1371/journal.pone.0132626
PMCID: PMC4526567

Genes

VWF
ABO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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