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Article

Effect of von Willebrand factor Y/C1584 on in vivo protein level and function and interaction with ABO blood group.

Blood - 1 Apr 2007

Davies James Anthony, Collins Peter William, Hathaway Lee Sarah, Bowen Derrick John

Abstract excerpt

Blood group O and the cysteine allele of the Y/C1584 change in von Willebrand factor (VWF) are enriched in type 1 VWD, but neither causes disease. We investigated the effect of C1584, alone and in combination with the ABO blood group, on the level and properties of plasma VWF. A cohort of 5052 blood donors was recruited: 50 donors were heterozygous for Y/C1584 and 5002 were homozygous for Y/Y1584. Mean VWF...

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Source

Identifiers

PMID: 17119126
DOI: 10.1182/blood-2006-07-035105

Genes

VWF
ABO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Effect of von Willebrand factor Y/C1584 on in vivo protein level and function and interaction with ABO blood group.PMID 17119126Read ↗

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