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Article

Pharmacogenomic or -epigenomic biomarkers in drug treatment: Two sides of the same medal?

Clinical pharmacology and therapeutics - 1 May 2016

Ingelman-Sundberg M, Cascorbi I

Abstract excerpt

Interindividual differences in expression of ADME genes are controlled by both genetic and epigenetic factors. Much emphasis has been made to describe the genetic influence, whereas the epigenetic part is not fully understood. Currently, we utilize mainly genetic biomarkers for optimization of drug therapy, although many rare genetic variants are not taken into consideration. Now, also epigenomic biomarkers are...

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PMID: 26874931
DOI: 10.1002/cpt.351

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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