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Article

Small activating RNA binds to the genomic target site in a seed-region-dependent manner.

Nucleic acids research - 18 Mar 2016

Meng Xing, Jiang Qian, Chang Nannan, Wang Xiaoxia, Liu Chujun, Xiong Jingwei, Cao Huiqing, Liang Zicai

Abstract excerpt

RNA activation (RNAa) is the upregulation of gene expression by small activating RNAs (saRNAs). In order to investigate the mechanism by which saRNAs act in RNAa, we used the progesterone receptor (PR) gene as a model, established a panel of effective saRNAs and assessed the involvement of the sense and antisense strands of saRNA in RNAa. All active saRNAs had their antisense strand effectively incorporated into...

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Identifiers

PMID: 26873922
DOI: 10.1093/nar/gkw076
PMCID: PMC4797303

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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