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Article

Steroid receptor RNA activator stimulates proliferation as well as apoptosis in vivo.

Molecular and cellular biology - 1 Oct 2003

Lanz Rainer B, Chua Steven S, Barron Niall, Söder Bettina M, DeMayo Francesco, O'Malley Bert W

Abstract excerpt

Steroid receptor RNA activator (SRA) is an RNA that coactivates steroid hormone receptor-mediated transcription in vitro. Its expression is strongly up-regulated in many human tumors of the breast, uterus, and ovary, suggesting a potential role in pathogenesis. To assess SRA function in vivo, a transgenic-mouse model was generated to enable robust human SRA expression by using the transcriptional activity of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 14517287
DOI: 10.1128/MCB.23.20.7163-7176.2003
PMCID: PMC230309

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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