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Article

Mutanome and expression of immune response genes in microsatellite stable colon cancer.

Oncotarget - 5 Apr 2016

Sanz-Pamplona Rebeca, Gil-Hoyos Raúl, López-Doriga Adriana, Alonso M Henar, Aussó Susanna, Molleví David G, Santos Cristina, Sanjuán Xavier, Salazar Ramón, Alemany Ramón, Moreno Víctor

Abstract excerpt

The aim of this study was to analyze the impact of the mutanome in the prognosis of microsatellite stable stage II CRC tumors. The exome of 42 stage II, microsatellite stable, colon tumors (21 of them relapse) and their paired mucosa were sequenced and analyzed. Although some pathways accumulated more mutations in patients exhibiting good or poor prognosis, no single somatic mutation was associated with...

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Identifiers

PMID: 26871478
DOI: 10.18632/oncotarget.7293
PMCID: PMC4951244

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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