Pathology of Mouse Models of Accelerated Aging.

doi:10.1177/0300985815625169

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Article

Pathology of Mouse Models of Accelerated Aging.

Veterinary pathology - 1 Mar 2016

Harkema L, Youssef S A, de Bruin A

Abstract excerpt

Progeroid mouse models display phenotypes in multiple organ systems that suggest premature aging and resemble features of natural aging of both mice and humans. The prospect of a significant increase in the global elderly population within the next decades has led to the emergence of "geroscience," which aims at elucidating the molecular mechanisms involved in aging. Progeroid mouse models are frequently used in...

Topics

Aging
Animals
Disease Models, Animal
Humans
Mice
Phenotype
Progeria

Source

Open in PubMed

Identifiers

PMID: 26864891
DOI: 10.1177/0300985815625169

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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