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Article

Comprehensive analysis of the MYB-NFIB gene fusion in salivary adenoid cystic carcinoma: Incidence, variability, and clinicopathologic significance.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Oct 2010

Mitani Yoshitsugu, Li Jie, Rao Pulivarthi H, Zhao Yi-Jue, Bell Diana, Lippman Scott M, Weber Randal S, Caulin Carlos, El-Naggar Adel K

Abstract excerpt

PURPOSE: The objectives of this study were to determine the incidence of the MYB-NFIB fusion in salivary adenoid cystic carcinoma (ACC), to establish the clinicopathologic significance of the fusion, and to analyze the expression of MYB in ACCs in the context of the MYB-NFIB fusion. EXPERIMENTAL DESIGN: We did an extensive analysis involving 123 cancers of the salivary gland, including primary and metastatic...

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Share to Carcinoma, Adenoid Cystic
Share to In Situ Hybridization, Fluorescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to NFI Transcription Factors

Share to Oncogene Proteins, Fusion

Share to Proto-Oncogene Proteins c-myb

Share to Reverse Transcriptase Polymerase Chain Reaction

Share to Salivary Gland Neoplasms

Source

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Identifiers

PMID: 20702610
DOI: 10.1158/1078-0432.CCR-10-0463
PMCID: PMC5862426

Genes

MYB
NFIB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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