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Article

Genomic Landscape of Somatic Alterations in Esophageal Squamous Cell Carcinoma and Gastric Cancer.

Cancer research - 1 Apr 2016

Hu Nan, Kadota Mitsutaka, Liu Huaitian, Abnet Christian C, Su Hua, Wu Hailong, Freedman Neal D, Yang Howard H, Wang Chaoyu, Yan Chunhua, Wang Lemin, Gere Sheryl, Hutchinson Amy, Song Guohong, Wang Yuan, Ding Ti, Qiao You-Lin, Koshiol Jill, Dawsey Sanford M, Giffen Carol, Goldstein Alisa M, Taylor Philip R, Lee Maxwell P

Abstract excerpt

Gastric cancer and esophageal cancer are the second and sixth leading causes of cancer-related death worldwide. Multiple genomic alterations underlying gastric cancer and esophageal squamous cell carcinoma (ESCC) have been identified, but the full spectrum of genomic structural variations and mutations have yet to be uncovered. Here, we report the results of whole-genome sequencing of 30 samples comprising tumor...

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Share to Carcinoma, Squamous Cell
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26857264
DOI: 10.1158/0008-5472.CAN-15-0338
PMCID: PMC4873357

Genes

GCA
AMH
BRCA2
CHEK2
ERBB2
FGF2
FHIT
JAK3
MACROD2
MNX1
MSH3
WNK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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