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Article

Impact of EGF, IL28B, and PNPLA3 polymorphisms on the outcome of allograft hepatitis C: a multicenter study.

Clinical transplantation - 1 Apr 2016

Mueller Jessica L, King Lindsay Y, Johnson Kara B, Gao Tian, Nephew Lauren D, Kothari Darshan, Simpson Mary Ann, Zheng Hui, Wei Lan, Corey Kathleen E, Misdraji Joseph, Lee Joon Hyoek, Lin M Valerie, Gogela Neliswa A, Fuchs Bryan C, Tanabe Kenneth K, Gordon Fredric D, Curry Michael P, Chung Raymond T

Abstract excerpt

Hepatitis C virus (HCV) infection is accelerated following liver transplantation (LT). Single nucleotide polymorphisms (SNPs) near the epidermal growth factor (EGF) (rs4444903), IL28B (rs12979860), and PNPLA3 (rs738409) loci are associated with treatment response, fibrosis, and hepatocellular carcinoma in non-transplant hepatitis C, but allograft population data are limited. We sought to determine the role of...

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Source

Open in PubMed Open full text

Identifiers

PMID: 26854475
DOI: 10.1111/ctr.12710
PMCID: PMC4868041

Genes

EGF
PNPLA3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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