Article
Donor PNPLA3 rs738409 genotype affects fibrosis progression in liver transplantation for hepatitis C.
Hepatology (Baltimore, Md.) - 1 Feb 2014
Dunn Winston, O'Neil Maura, Zhao Jie, Wu Chuang Hong, Roberts Benjamin, Chakraborty Shweta, Sherman Craig, Weaver Brandy, Taylor Ryan, Olson Jody, Olyaee Mojtaba, Gilroy Richard, Schmitt Timothy, Wan Yu-Jui Yvonne, Weinman Steven A
Abstract excerpt
UNLABELLED: The rs738409 G>C single nucleotide polymorphism occurring in the patatin-like phospholipase 3 gene has been identified as a novel genetic marker for hepatic steatosis. Recent studies also associated rs738409 with fibrosis in hepatitis C (HCV). Therefore, we sought to determine the impact of donor and recipient rs738409 genotype on the progression of fibrosis after liver transplantation for HCV. This...
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