Article
Association between the epidermal growth factor rs4444903 G/G genotype and advanced fibrosis at a young age in chronic hepatitis C.
Cytokine - 1 Jan 2012
Falleti Edmondo, Cmet Sara, Fabris Carlo, Bitetto Davide, Cussigh Annarosa, Fornasiere Ezio, Bignulin Eleonora, Feruglio Cristina, Mosanghini Elena, Fontanini Elisabetta, Pirisi Mario, Toniutto Pierluigi
Abstract excerpt
BACKGROUND: The epidermal growth factor (EGF) rs4444903 A>G polymorphism has been associated with the development of liver cancer, which commonly complicates cirrhosis of viral origin; however, whether this polymorphism might be associated with fibrosis progression in chronic viral hepatitis is unknown. The present study was performed to assess the allelic and genotypic frequencies of the rs4444903 A>G...
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