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Article

Impact of IL28B-related single nucleotide polymorphisms on liver histopathology in chronic hepatitis C genotype 2 and 3.

PloS one - 1 Jan 2012

Rembeck Karolina, Alsiö Asa, Christensen Peer Brehm, Färkkilä Martti, Langeland Nina, Buhl Mads Rauning, Pedersen Court, Mørch Kristine, Westin Johan, Lindh Magnus, Hellstrand Kristoffer, Norkrans Gunnar, Lagging Martin

Abstract excerpt

BACKGROUND AND AIMS: Recently, several genome-wide association studies have revealed that single nucleotide polymorphisms (SNPs) in proximity to IL28B predict spontaneous clearance of HCV infection as well as outcome following peginterferon and ribavirin therapy among HCV genotype 1 infected patients. The present study aimed to evaluate the impact of IL28B SNP variability on liver histology in the context of a...

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Identifiers

PMID: 22253715
DOI: 10.1371/journal.pone.0029370
PMCID: PMC3258245

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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