Article
Genetic Polymorphism of Epidermal Growth Factor rs4444903 Influences Susceptibility to HCV-Related Liver Cirrhosis and Hepatocellular Carcinoma in a Chinese Han Population.
Clinical laboratory - 1 Apr 2017
Zhang Shitian, Qiao Kunyan, Trieu Congdoanh, Huo Zhixiao, Dai Qinghai, Du Yanan, Lu Wei, Hou Wei
Abstract excerpt
BACKGROUND: Genetic polymorphism in the epidermal growth factor (EGF, rs4444903) gene has been demonstrated to be associated with the clinical deterioration in hepatitis C virus (HCV)-related liver cirrhosis (LC) and the development of hepatocellular carcinoma (HCC). Whether this single nucleotide polymorphism (SNP) influences susceptibility to HCV-related LC and HCC in the Chinese Han population is largely...
Topics
- Carcinoma, Hepatocellular
- Case-Control Studies
- EGF Family of Proteins
- Genetic Predisposition to Disease
- Genotype
- Hepacivirus
- Humans