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Article

Association analysis of COMT polymorphisms with schizophrenia and smooth pursuit eye movement abnormality.

Journal of human genetics - 1 Dec 2009

Park Byung Lae, Shin Hyoung Doo, Cheong Hyun Sub, Park Chul Soo, Sohn Jin-Wook, Kim Bong-Jo, Seo Han-Kil, Kim Jae Won, Kim Ki-Hoon, Shin Tae-Min, Choi Ihn-Geun, Kim Shin Gyeom, Woo Sung-Il

Abstract excerpt

Schizophrenia is a multifactorial disorder characterized by the contribution of multiple susceptibility genes that may act in conjunction with epigenetic processes and environmental factors. The catechol-O-methyltransferase (COMT) gene, which is located in the 22q11 microdeletion, has been considered as a candidate gene for schizophrenia because of its ability to degrade catecholamines, including dopamine. In a...

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Source

Identifiers

PMID: 19881467
DOI: 10.1038/jhg.2009.102

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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