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Article

Genome-wide association study of serum iron phenotypes in premenopausal women of European descent.

Blood cells, molecules & diseases - 1 Mar 2016

Koller Daniel L, Imel Erik A, Lai Dongbing, Padgett Leah R, Acton Dena, Gray Amie, Peacock Munro, Econs Michael J, Foroud Tatiana

Abstract excerpt

A genome-wide association study was performed on 1130 premenopausal women to detect common variants associated with three serum iron-related phenotypes. Total iron binding capacity was strongly associated (p=10(-14)) with variants in and near the TF gene (transferrin), the serum iron transporting protein, and with variants in HFE (p=4×10(-7)), which encodes the human hemochromatosis gene. Association was also...

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Source

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Identifiers

PMID: 26852655
DOI: 10.1016/j.bcmd.2015.12.002
PMCID: PMC4746500

Genes

HFE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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