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Associations of genetically determined iron status across the phenome: A mendelian randomization study

20 Jun 2019

Abstract excerpt

BACKGROUND: Iron is integral to many physiological processes, and variations in its levels, even within the normal range, can have implications for health. The objective of this study was to explore the broad clinical effects of varying iron status. METHODS AND FINDINGS: Genome-wide association study (GWAS) summary data obtained from 48,972 European individuals (55% female) across 19 cohorts in the Genetics of...

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PMID: 31220083
DOI: 10.1371/journal.pmed.1002833

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