Article
Genome-wide association study identifies genetic loci associated with iron deficiency.
PloS one - 31 Mar 2011
McLaren Christine E, Garner Chad P, Constantine Clare C, McLachlan Stela, Vulpe Chris D, Snively Beverly M, Gordeuk Victor R, Nickerson Debbie A, Cook James D, Leiendecker-Foster Catherine, Beckman Kenneth B, Eckfeldt John H, Barcellos Lisa F, Murray Joseph A, Adams Paul C, Acton Ronald T, Killeen Anthony A, McLaren Gordon D
Abstract excerpt
The existence of multiple inherited disorders of iron metabolism in man, rodents and other vertebrates suggests genetic contributions to iron deficiency. To identify new genomic locations associated with iron deficiency, a genome-wide association study (GWAS) was performed using DNA collected from white men aged≥25 y and women≥50 y in the Hemochromatosis and Iron Overload Screening (HEIRS) Study with serum...
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