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Article

Variants in TF and HFE explain approximately 40% of genetic variation in serum-transferrin levels.

American journal of human genetics - 1 Jan 2009

Benyamin Beben, McRae Allan F, Zhu Gu, Gordon Scott, Henders Anjali K, Palotie Aarno, Peltonen Leena, Martin Nicholas G, Montgomery Grant W, Whitfield John B, Visscher Peter M

Abstract excerpt

Only a small proportion of genetic variation in complex traits has been explained by SNPs from genome-wide association studies (GWASs). We report the results from two GWASs for serum markers of iron status (serum iron, serum transferrin, transferrin saturation with iron, and serum ferritin), which are important in iron overload (e.g., hemochromatosis) and deficiency (e.g., anemia) conditions. We performed two...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19084217
DOI: 10.1016/j.ajhg.2008.11.011
PMCID: PMC2668053

Genes

HFE

Provenance

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Related research

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Variants in TF and HFE explain approximately 40% of genetic variation in serum-transferrin levels.PMID 19084217Read ↗

Genome-wide association study identifies TF as a significant modifier gene of iron metabolism in HFE hemochromatosis.Semantic proximity Read ↗

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