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Article

Associations between single nucleotide polymorphisms in iron-related genes and iron status in multiethnic populations.

PloS one - 1 Jan 2012

McLaren Christine E, McLachlan Stela, Garner Chad P, Vulpe Chris D, Gordeuk Victor R, Eckfeldt John H, Adams Paul C, Acton Ronald T, Murray Joseph A, Leiendecker-Foster Catherine, Snively Beverly M, Barcellos Lisa F, Cook James D, McLaren Gordon D

Abstract excerpt

The existence of multiple inherited disorders of iron metabolism suggests genetic contributions to iron deficiency. We previously performed a genome-wide association study of iron-related single nucleotide polymorphisms (SNPs) using DNA from white men aged ≥ 25 y and women ≥ 50 y in the Hemochromatosis and Iron Overload Screening (HEIRS) Study with serum ferritin (SF) ≤ 12 µg/L (cases) and controls (SF >100 µg/L...

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Identifiers

PMID: 22761678
DOI: 10.1371/journal.pone.0038339
PMCID: PMC3382217

Genes

TMPRSS6
CUBN

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