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Article

Genome-wide association study identifies TF as a significant modifier gene of iron metabolism in HFE hemochromatosis.

Journal of hepatology - 1 Mar 2015

de Tayrac Marie, Roth Marie-Paule, Jouanolle Anne-Marie, Coppin Hélène, le Gac Gérald, Piperno Alberto, Férec Claude, Pelucchi Sara, Scotet Virginie, Bardou-Jacquet Edouard, Ropert Martine, Bouvet Régis, Génin Emmanuelle, Mosser Jean, Deugnier Yves

Abstract excerpt

BACKGROUND & AIMS: Hereditary hemochromatosis (HH) is the most common form of genetic iron loading disease. It is mainly related to the homozygous C282Y/C282Y mutation in the HFE gene that is, however, a necessary but not a sufficient condition to develop clinical and even biochemical HH. This su...

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Source

Identifiers

PMID: 25457201
DOI: 10.1016/j.jhep.2014.10.017

Genes

HFE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25457201-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Genome-wide association study identifies TF as a significant modifier gene of iron metabolism in HFE hemochromatosis.PMID 25457201Read ↗

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