Article
A TET2 rs3733609 C/T genotype is associated with predisposition to the myeloproliferative neoplasms harboring JAK2(V617F) and confers a proliferative potential on erythroid lineages.
Oncotarget - 23 Feb 2016
Shen Xiao-hui, Sun Nan-nan, Yin Ya-fei, Liu Su-fang, Liu Xiao-liu, Peng Hong-ling, Dai Chong-wen, Xu Yun-xiao, Deng Ming-yang, Luo Yun-ya, Zheng Wen-li, Zhang Guang-sen
Abstract excerpt
Common germline single-nucleotide polymorphisms (SNPs) at JAK2 locus have been associated with Myeloproliferative neoplasms (MPN). And, the germline sequence variant rs2736100 C in TERT is related to risk of MPN, suggesting a complex association between SNPs and the pathogenesis of MPN. Our previous study (unpublished data) showed that there was a high frequency distribution in rs3733609 C/T genotype at...
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