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Article

The role of the JAK2 GGCC haplotype and the TET2 gene in familial myeloproliferative neoplasms.

Haematologica - 1 Mar 2011

Olcaydu Damla, Rumi Elisa, Harutyunyan Ashot, Passamonti Francesco, Pietra Daniela, Pascutto Cristiana, Berg Tiina, Jäger Roland, Hammond Emma, Cazzola Mario, Kralovics Robert

Abstract excerpt

BACKGROUND: Myeloproliferative neoplasms constitute a group of diverse chronic myeloid malignancies that share pathogenic features such as acquired mutations in the JAK2, TET2, CBL and MPL genes. There are recent reports that a JAK2 gene haplotype (GGCC or 46/1) confers susceptibility to JAK2 mut...

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Source

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Identifiers

PMID: 21173100
DOI: 10.3324/haematol.2010.034488
PMCID: PMC3046267

Genes

JAK2
TET2
CBL
MPL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21173100-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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