Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Activation‐Induced Killer Cell Immunoglobulin‐like Receptor 3DL2 Binding to HLA–B27 Licenses Pathogenic T Cell Differentiation in Spondyloarthritis

25 Nov 2015

Abstract excerpt

OBJECTIVE: In the spondyloarthritides (SpA), increased numbers of CD4+ T cells express killer cell immunoglobulin-like receptor 3DL2 (KIR-3DL2). The aim of this study was to determine the factors that induce KIR-3DL2 expression, and to characterize the relationship between HLA-B27 and the phenotype and function of KIR-3DL2-expressing CD4+ T cells in SpA. METHODS: In total, 34 B27+ patients with SpA, 28 age- and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autoimmune and Inflammatory Disorders Research
Share to Immune Cell Function and Interaction
Share to Spondyloarthritis Studies and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26841353
DOI: 10.1002/art.39515

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Activation‐Induced Killer Cell Immunoglobulin‐like Receptor 3DL2 Binding to HLA–B27 Licenses Pathogenic T Cell Differentiation in SpondyloarthritisPMID 26841353Read ↗

Killer immunoglobulin receptor genes in spondyloarthritis.Semantic proximity Read ↗

AxSpA joint tissue is characterised by HLA-DR <sup>+</sup> tissue resident memory (TRM) and killer cell immunoglobulin-like receptor (KIR) <sup>+</sup> CD8 <sup>+</sup> T cell subsetsSemantic proximity Read ↗

Epistatic interactions between killer immunoglobulin-like receptors and human leukocyte antigen ligands are associated with ankylosing spondylitis.Semantic proximity Read ↗

Polymorphic KIR3DL3 expression modulates tissue-resident and innate-like T cellsSemantic proximity Read ↗

Ankylosing Spondylitis: From Cells to GenesSemantic proximity Read ↗

Polymorphisms of KIR gene and HLA-C alleles: possible association with susceptibility to HLA-B27-positive patients with ankylosing spondylitis.Semantic proximity Read ↗

Study on the protective effect of the KIR3DL1 gene in ankylosing spondylitis.Semantic proximity Read ↗

Human Leukocyte Antigen C*12:02:02 and Killer Immunoglobulin-Like Receptor 2DL5 are Distinctly Associated with Ankylosing Spondylitis in the Taiwanese.Semantic proximity Read ↗

Antigen-specific immune reactions by expanded CD8+ T cell clones from HLA-B*27-positive patients with spondyloarthritisSemantic proximity Read ↗

KIR genes and their role in spondyloarthropathies.Semantic proximity Read ↗

Enhanced cytotoxicity of aging associated NKG2C + CD8 + T cells in ankylosing spondylitis via HLA-B27Semantic proximity Read ↗

Killer cell immunoglobulin-like receptors in HLA-B27-associated acute anterior uveitis, with and without axial spondyloarthropathy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.