Article
KIR genes and their role in spondyloarthropathies.
Advances in experimental medicine and biology - 1 Jan 2009
Díaz-Peña Roberto, Blanco-Gelaz Miguel Angel, López-Larrea Carlos
Abstract excerpt
Cellular activity of natural killer cells (NK cells) is defined by the balance between activating and inhibitory signals coming from their receptors. With respect to this response, killer immunoglobulin-like receptors (KIR) are unique because of their diversity and capacity to recognize specific human leukocyte antigen (HLA) class I allotypes. Up to the present few studies have experimentally been developed...
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