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Ankylosing Spondylitis: From Cells to Genes

1 Jan 2013

Abstract excerpt

Ankylosing spondylitis (AS) is a chronic inflammatory disease of unknown etiology, though it is considered an autoimmune disease. HLA-B27 is the risk factor most often associated with AS, and although the mechanism of involvement is unclear, the subtypes and other features of the relationship between HLA-B27 and AS have been studied for years. Additionally, the key role of IL-17 and Th17 cells in autoimmunity and...

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PMID: 23970995
DOI: 10.1155/2013/501653

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