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Article

Looking for Neuroimaging Markers in Frontotemporal Lobar Degeneration Clinical Trials: A Multi-Voxel Pattern Analysis Study in Granulin Disease.

Journal of Alzheimer's disease : JAD - 1 Jan 2016

Premi Enrico, Cauda Franco, Costa Tommaso, Diano Matteo, Gazzina Stefano, Gualeni Vera, Alberici Antonella, Archetti Silvana, Magoni Mauro, Gasparotti Roberto, Padovani Alessandro, Borroni Barbara

Abstract excerpt

In light of future pharmacological interventions, neuroimaging markers able to assess the response to treatment would be crucial. In Granulin (GRN) disease, preclinical data will prompt pharmacological trials in the future. Two main points need to be assessed: (1) to identify target regions in different disease stages and (2) to determine the most accurate functional and structural neuroimaging index to be used....

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PMID: 26836150
DOI: 10.3233/JAD-150340

Genes

GRN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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