Article
Copy number loss of variation_91720 in PIK3CA predicts risk of esophageal squamous cell carcinoma.
International journal of clinical and experimental pathology - 1 Jan 2015
Wu Yuanyuan, Liu Xi, Hu Liwen, Tao Huansheng, Guan Xingying, Zhang Kun, Bai Yun, Yang Kang
Abstract excerpt
PURPOSE: Esophageal squamous cell carcinoma (ESCC) is one of the most fatal cancers worldwide. However, the etiology is complex and unclear. 3q26 harboring abundant oncogenes have been identified as the loci of ESCC susceptibility. In the present study, we examined whether CNVs on 3q26 would be associated with the risk, TNM stage and prognosis of ESCC. METHODS: Variation_91720 in phosphatidylinositol 3-kinase...
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