Article
ABCC4 copy number variation is associated with susceptibility to esophageal squamous cell carcinoma.
Carcinogenesis - 1 Sept 2014
Sun Yulin, Shi Ni, Lu Haizhen, Zhang Jinqiang, Ma Yulong, Qiao Yuanyuan, Mao Yonghong, Jia Kun, Han Lifen, Liu Fang, Li Hongxia, Lin Zhengwei, Li Xinmin, Zhao Xiaohang
Abstract excerpt
Esophageal squamous cell carcinoma (ESCC) is the eighth most common cause of cancer-related death worldwide. However, previous genome-wide single nucleotide polymorphism association analyses have not explained the high heritability associated with ESCC. In this study, we performed genome-wide copy number variation (CNV) analysis on 128 discordant sibling pairs to identify novel genes that contribute to ESCC...
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