Article
Single-nucleotide polymorphism-mass array reveals commonly deleted regions at 3p22 and 3p14.2 associate with poor clinical outcome in esophageal squamous cell carcinoma.
International journal of cancer - 15 Aug 2008
Qin Yan Ru, Fu Li, Sham Pak C, Kwong Dora L W, Zhu Cai Lei, Chu Kevin K W, Li Yan, Guan Xin-Yuan
Abstract excerpt
Esophageal squamous cell carcinoma (ESCC) is one of the most common solid tumors in the world with poor prognosis. Deletion of chromosome 3p is one of the most frequent chromosomal alterations in ESCC, suggesting the existence of one or more tumor suppressor genes (TSGs) at this region. In the present study, a recently developed high-throughput and high-resolution technology, single-nucleotide polymorphism...
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