Article
Influence of MX1 promoter rs2071430 G/T polymorphism on susceptibility to systemic lupus erythematosus.
Clinical rheumatology - 1 Mar 2016
AlFadhli Suad, Al-Mutairi Mashael, Al Tameemi Bader, Nizam Rasheeba
Abstract excerpt
The expression of interferon inducible genes are reported to be heightened in systemic lupus erythematosus (SLE); nevertheless, not much is known regarding the genetic variants underlying these genes and their role in the pathogenesis of disease. Herein, we aim to explore the potential association and contribution of polymorphisms in MX1 gene (i) promoter with part of exon 1 (ii) intron 6, and (iii) their...
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