Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of interferon-gamma gene polymorphism (+874A) with arthritis manifestation in SLE.

Clinical rheumatology - 1 Nov 2007

Tangwattanachuleeporn Marut, Sodsai Pimpayao, Avihingsanon Yingyos, Wongpiyabovorn Jongkonnee, Wongchinsri Jeerapat, Hirankarn Nattiya

Abstract excerpt

Systemic lupus erythematosus (SLE) is a complex autoimmune disease in which genetic factors strongly influence susceptibility. Cytokines such as the interferon-gamma (IFNG) gene play a key role in controlling the immunity and inflammation, and therefore their polymorphisms may affect these genes' expression levels among individuals. We investigated the frequency of IFNG gene intron (+874) polymorphism, previously...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arthritis
Share to Autoimmune Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation

Share to Genes, Dominant

Share to Interferon-gamma

Share to Introns

Share to Lupus Erythematosus, Systemic

Share to Thailand

Source

Identifiers

PMID: 17713715
DOI: 10.1007/s10067-007-0699-6

Genes

IFNG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of interferon-gamma gene polymorphism (+874A) with arthritis manifestation in SLE.PMID 17713715Read ↗

Interferon-gamma (IFN-γ) intronic variant (rs2430561) is a risk factor for systemic lupus erythematosus: Observation from a meta-analysis.Semantic proximity Read ↗

Association between the interferon-γ +874 T/A polymorphism and susceptibility to systemic lupus erythematosus and rheumatoid arthritis: A meta-analysis.Semantic proximity Read ↗

Association of IL-18 gene polymorphism (-137C) with arthritis manifestations in SLE: combined effect with IFN gamma gene polymorphism (+874A).Semantic proximity Read ↗

Interferon-gamma gene polymorphisms associated with susceptibility to systemic lupus erythematosus.Semantic proximity Read ↗

The interferon-gamma receptor gene polymorphisms (Val14Met and Gln64Arg) are not associated with systemic lupus erythematosus in Chinese patients.Semantic proximity Read ↗

Genetic polymorphisms in genes involved in the type I interferon system (STAT4 and IRF5): association with Asian SLE patients.Semantic proximity Read ↗

A meta-analysis of the association of IL-6 -174 G/C and -572 G/C polymorphisms with systemic lupus erythematosus risk.Semantic proximity Read ↗

Variations in the interferon and TLR3 genes may be associated with susceptibility to systemic lupus erythematosus and its clinical presentation.Semantic proximity Read ↗

Genetic susceptibility to SLE is associated with TNF-alpha gene polymorphism -863, but not -308 and -238, in Thai population.Semantic proximity Read ↗

Association between interferon-γ +874 T/A polymorphism and susceptibility to autoimmune diseases: a meta-analysis.Semantic proximity Read ↗

Effect of Interferon-γ Polymorphisms on Ankylosing Spondylitis: A Case-Control Study.Semantic proximity Read ↗

Interleukin 4 and STAT6 gene polymorphisms are associated with systemic lupus erythematosus in Chinese patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.