Article
Interleukin-18 promoter polymorphisms in patients with systemic lupus erythematosus.
Clinical and experimental rheumatology - 1 Jan 2000
Warchoł T, Lianeri M, Olesińska M, Jagodziński P P
Abstract excerpt
OBJECTIVES: The role of various polymorphisms located in the IL-18 promoter has not yet been defined with regards to patient susceptibility to SLE, and occurrence of clinical manifestations of the disease remains inconsistent. METHODS: Using PCR-RFLP and DNA sequencing analysis we studied the frequency of -137 G/C (rs187238), -607 C/A (rs1946518) and -1297C/T (rs360719) polymorphisms in IL-18 promoter in patients...
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