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Article

Single nucleotide polymorphisms and functional analysis of MxA promoter region in multiple sclerosis.

Journal of the neurological sciences - 15 Nov 2006

Furuyama Hiroyasu, Chiba Susumu, Okabayashi Tamaki, Yokota Shin-ichi, Nonaka Michio, Imai Tomihiro, Fujii Nobuhiro, Matsumoto Hiroyuki

Abstract excerpt

OBJECTIVE: Interferons (IFNs)-inducible myxovirus resistance protein A (MxA) has recently been used as an indirect marker of neutralizing antibody against IFN in patients with multiple sclerosis (MS). On the other hand, MxA inhibits the replication of viruses by means of modifying cellular function, including apoptotic pathway. Our objective is to investigate the genetic and pathological role of MxA in patients...

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Identifiers

PMID: 16843495
DOI: 10.1016/j.jns.2006.06.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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