Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interaction between Methylation and CpG Single-Nucleotide Polymorphisms in the HTR2A Gene: Association Analysis with Suicide Attempt in Schizophrenia.

Neuropsychobiology - 1 Jan 2016

Bani-Fatemi Ali, Howe Aaron S, Matmari Michelle, Koga Arthur, Zai Clement, Strauss John, De Luca Vincenzo

Abstract excerpt

Dysfunctional mechanisms in the serotonergic system have been implicated in suicidal behavior among patients with schizophrenia. However, previous association analyses of major serotonin genes have provided inconsistent findings regarding their role in suicidal behavior. The goal of the current study was to identify single-nucleotide polymorphisms (SNP) within HTR2A that directly affect CpG methylation sites in...

Topics

Adult
CpG Islands
DNA Methylation
Epigenesis, Genetic
Female
Genetic Association Studies
Humans
Male
Middle Aged
Polymorphism, Single Nucleotide
Receptor, Serotonin, 5-HT2A

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Schizophrenia

Suicide, Attempted

Source

Identifiers

PMID: 26812280
DOI: 10.1159/000441191

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-26812280-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interaction between Methylation and CpG Single-Nucleotide Polymorphisms in the HTR2A Gene: Association Analysis with Suicide Attempt in Schizophrenia.PMID 26812280Read ↗

Multiple tissue methylation analysis of HTR2A exon I in suicidal behavior.Semantic proximity Read ↗

Association and CpG SNP analysis of HTR4 polymorphisms with suicidal behavior in subjects with schizophrenia.Semantic proximity Read ↗

Analysis of CpG SNPs in 34 genes: association test with suicide attempt in schizophrenia.Semantic proximity Read ↗

Investigating the relationship between DNA methylation, genetic variation, and suicide attempt in bipolar disorderSemantic proximity Read ↗

Investigating the Relationship Between DNA Methylation, Genetic Variation, and Suicide Attempt in Bipolar Disorder.Semantic proximity Read ↗

Hypomethylation of the serotonin receptor type-2A Gene (HTR2A) at T102C polymorphic site in DNA derived from the saliva of patients with schizophrenia and bipolar disorder.Semantic proximity Read ↗

Methylation and QTDT analysis of the 5-HT2A receptor 102C allele: analysis of suicidality in major psychosis.Semantic proximity Read ↗

Effects of DNA methylation and polygenic scores on self-reported suicidal ideation in psychoses: no evidence of epigenetic basis of polygenic risk.Semantic proximity Read ↗

The role of tyrosine hydroxylase gene variants in suicide attempt in schizophrenia.Semantic proximity Read ↗

Epigenetic dysregulation of HTR2A in the brain of patients with schizophrenia and bipolar disorder.Semantic proximity Read ↗

Association of the 5HTR2A gene with suicidal behavior: case-control study and updated meta-analysis.Semantic proximity Read ↗

Genetic variation in DNMT3B and increased global DNA methylation is associated with suicide attempts in psychiatric patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.