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Article

Multiple tissue methylation analysis of HTR2A exon I in suicidal behavior.

Psychiatric genetics - 1 Dec 2017

Bani-Fatemi Ali, Strauss John, Zai Clement, Wong Albert H C, de Luca Vincenzo

Abstract excerpt

OBJECTIVE: The main aim of the current study was to investigate epigenetic alterations in serotonin 2A receptor (HTR2A) exon I CpG sites as possible risk factors for suicidal behavior. We also aimed to analyze the epigenetic alterations in two different tissues as epigenetic mechanisms are tissue specific. These epigenetic changes may lead to a better prediction of suicidal behavior. METHODS: Direct CpG...

Topics

Adult
Bipolar Disorder
DNA Methylation
Epigenesis, Genetic
Exons
Genetic Predisposition to Disease
Humans
Male
Polymorphism, Single Nucleotide
Promoter Regions, Genetic
Receptor, Serotonin, 5-HT2A

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Schizophrenia

Self-Injurious Behavior

Suicidal Ideation

Suicide

Suicide, Attempted

Source

Identifiers

PMID: 29068870
DOI: 10.1097/YPG.0000000000000183

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-29068870-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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