Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Methylation and QTDT analysis of the 5-HT2A receptor 102C allele: analysis of suicidality in major psychosis.

Journal of psychiatric research - 1 Feb 2009

De Luca Vincenzo, Viggiano Emanuela, Dhoot Ranbir, Kennedy James L, Wong Albert H C

Abstract excerpt

Suicide is an act deliberately initiated and performed by a person with full knowledge that a fatal outcome is probable. The serotonin 2A (5-HT2A) receptor gene has been implicated in the pathogenesis of suicidal behaviour by a genetic association between the 5-HT2A T102C silent polymorphism and suicidality in patients with mood disorders and schizophrenia. However, a recent meta-analysis failed to confirm this...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bipolar Disorder
Share to Leukocytes

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Methylation

Share to Prefrontal Cortex

Share to Psychotic Disorders

Share to Receptor, Serotonin, 5-HT2A

Share to Schizophrenic Psychology

Share to Suicide

Source

Identifiers

PMID: 18783799
DOI: 10.1016/j.jpsychires.2008.07.007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Methylation and QTDT analysis of the 5-HT2A receptor 102C allele: analysis of suicidality in major psychosis.PMID 18783799Read ↗

Differential expression and parent-of-origin effect of the 5-HT2A receptor gene C102T polymorphism: analysis of suicidality in schizophrenia and bipolar disorder.Semantic proximity Read ↗

Multiple tissue methylation analysis of HTR2A exon I in suicidal behavior.Semantic proximity Read ↗

Association study of T102C 5-HT(2A) polymorphism in schizophrenic patients: diagnosis, psychopathology, and suicidal behavior.Semantic proximity Read ↗

Interaction between Methylation and CpG Single-Nucleotide Polymorphisms in the HTR2A Gene: Association Analysis with Suicide Attempt in Schizophrenia.Semantic proximity Read ↗

Lack of association of serotonin-2A receptor gene polymorphism (T102C) with suicidal ideation and suicide.Semantic proximity Read ↗

5-HT2C receptor and MAO-A interaction analysis: no association with suicidal behaviour in bipolar patients.Semantic proximity Read ↗

Hypomethylation of the serotonin receptor type-2A Gene (HTR2A) at T102C polymorphic site in DNA derived from the saliva of patients with schizophrenia and bipolar disorder.Semantic proximity Read ↗

The 5-HT(2A) receptor gene 102T/C polymorphism is associated with suicidal behavior in depressed patients.Semantic proximity Read ↗

Parent-of-origin effect and genomic imprinting of the HTR2A receptor gene T102C polymorphism in psychosis.Semantic proximity Read ↗

Parent of origin effect and allelic expression imbalance of the serotonin transporter in bipolar disorder and suicidal behaviour.Semantic proximity Read ↗

Association of the T102C polymorphism in the HTR2A gene with major depressive disorder, bipolar disorder, and schizophrenia.Semantic proximity Read ↗

Association of polymorphism of serotonin 2A receptor gene with suicidal ideation in major depressive disorder.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.