Article
Association and CpG SNP analysis of HTR4 polymorphisms with suicidal behavior in subjects with schizophrenia.
Journal of neural transmission (Vienna, Austria : 1996) - 1 Feb 2013
Polsinelli Gina, Zai Clement C, Strauss John, Kennedy James L, De Luca Vincenzo
Abstract excerpt
Suicide is a major contributor to the morbidity and mortality rates in schizophrenia. Genetic and epigenetic factors have been reported to modulate the risk for suicide although the precise mechanism and magnitude of these contributions is unknown. Previous research indicates that suicide attempters present abnormalities in the serotonergic system. The present study aimed to identify genetic and epigenetic risk...
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