Article
The prognostic significance of the BRAF V600E mutation in papillary thyroid carcinoma detected by mutation-specific immunohistochemistry.
Pathology - 1 Dec 2013
McKelvie Penelope A, Chan Fiona, Yu Yong, Waring Paul, Gresshoff Irma, Farrell Stephen, Williams Richard A
Abstract excerpt
AIMS: BRAF mutation has been shown in a large meta-analysis to be an independent prognostic marker for papillary thyroid carcinoma (PTC) with poorer survival and higher recurrence rates. METHODS: We studied prevalence of BRAF mutation in 77 patients with PTC from an Australian cohort using competitive polymerase chain reaction (C-PCR) and immunohistochemistry (IHC) with BRAF-specific antibody, VE1....
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