Article
CaMKII phosphorylates collapsin response mediator protein 2 and modulates axonal damage during glutamate excitotoxicity.
Journal of neurochemistry - 1 Nov 2009
Hou Sheng T, Jiang Susan X, Aylsworth Amy, Ferguson Graeme, Slinn Jacqueline, Hu Houwen, Leung Thomas, Kappler Joachim, Kaibuchi Kozo
Abstract excerpt
Intracellular calcium influx through NMDA receptors triggers a cascade of deleterious signaling events which lead to neuronal death in neurological conditions such as stroke. However, it is not clear as to the molecular mechanism underlying early damage response from axons and dendrites which are...
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