Back to search

Article

Reduced axonal caliber and white matter changes in a rat model of Fragile X syndrome with a deletion of a K Homology domain of <i>Fmr1</i>

2019-12-04

Abstract excerpt

Fragile X syndrome (FXS) is a neurodevelopmental disorder that is caused by mutations in the FMR1 gene that are known to cause neuroanatomical alterations. The morphological underpinnings of these alterations have not been elucidated. Furthermore, while alterations have been identified in both male and female individuals, neuroanatomy in female rodent models has not been assessed. We identified structural differe...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
49e45037-0a90-53bb-8b0d-5fab802acbcc
DOI
10.1101/864371
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Reduced axonal caliber and white matter changes in a rat model of Fragile X syndrome with a deletion of a K Homology domain of <i>Fmr1</i>DOI 10.1101/864371
Regional brain volumes changes in adult male FMR1-KO mouse on the FVB strain.Semantic proximity
Neuroanatomical, molecular genetic, and behavioral correlates of fragile X syndrome.Semantic proximity
Anatomical phenotyping in a mouse model of fragile X syndrome with magnetic resonance imaging.Semantic proximity
Specific effect of the fragile-X mental retardation-1 gene (FMR1) on white matter microstructure.Semantic proximity
White matter tract alterations in fragile X syndrome: Preliminary evidence from diffusion tensor imagingSemantic proximity
In vivo brain anatomy of adult males with Fragile X syndrome: an MRI study.Semantic proximity
Effects of Fmr1 Gene Mutations on Sex Differences in Autism-Like Behavior and Dendritic Spine Development in Mice and Transcriptomic Studies.Semantic proximity
Reduced Brain Volume and White Matter Alterations in Shank3-Deficient RatsSemantic proximity
Analysis of FMR1 deletion in a subpopulation of post-mitotic neurons in mouse cortex and hippocampus.Semantic proximity
Disruption of the KH1 domain of <i>Fmr1</i> leads to transcriptional alterations and attentional deficits in ratsSemantic proximity
Correlates across the structural, functional, and molecular phenotypes of fragile X syndrome.Semantic proximity
A mouse model of the fragile X premutation: effects on behavior, dendrite morphology, and regional rates of cerebral protein synthesis.Semantic proximity
Select a neighboring publication to make it the new centre.