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Article

Anatomical phenotyping in a mouse model of fragile X syndrome with magnetic resonance imaging.

NeuroImage - 15 Nov 2010

Ellegood Jacob, Pacey Laura K, Hampson David R, Lerch Jason P, Henkelman R Mark

Abstract excerpt

Fragile X Syndrome (FXS) is the most common single gene cause of inherited mental impairment, and cognitive deficits can range from simple learning disabilities to mental retardation. Human FXS is caused by a loss of the Fragile X Mental Retardation Protein (FMRP). The fragile X knockout (FX KO) mouse also shows a loss of FMRP, as well as many of the physical and behavioural characteristics of human FXS. This...

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Share to Fragile X Mental Retardation Protein
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20304074
DOI: 10.1016/j.neuroimage.2010.03.038

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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