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Article

Region-specific alterations in brain development in one- to three-year-old boys with fragile X syndrome.

Proceedings of the National Academy of Sciences of the United States of America - 18 May 2010

Hoeft Fumiko, Carter John C, Lightbody Amy A, Cody Hazlett Heather, Piven Joseph, Reiss Allan L

Abstract excerpt

Longitudinal neuroimaging investigation of fragile X syndrome (FXS), the most common cause of inherited intellectual disability and autism, provides an opportunity to study the influence of a specific genetic factor on neurodevelopment in the living human brain. We examined voxel-wise gray and white matter volumes (GMV, WMV) over a 2-year period in 1- to 3-year-old boys with FXS (n = 41) and compared these...

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Identifiers

PMID: 20439717
DOI: 10.1073/pnas.1002762107
PMCID: PMC2889103

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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