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Article

Analysis of the potential of cancer cell lines to release tissue factor-containing microvesicles: correlation with tissue factor and PAR2 expression

19 Jan 2016

Abstract excerpt

BACKGROUND: Despite the association of cancer-derived circulating tissue factor (TF)-containing microvesicles and hypercoagulable state, correlations with the incidence of thrombosis remain unclear. METHODS: In this study the upregulation of TF release upon activation of various cancer cell lines, and the correlation with TF and PAR2 expression and/or activity was examined. Microvesicle release was induced by...

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Share to Blood Coagulation and Thrombosis Mechanisms
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PMID: 26793031
DOI: 10.1186/s12959-016-0075-3

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